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butalbital will minimize the extent or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.fedratinib will boost the degree or effect of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Observe. Regulate dose of medication that happen to be CYP2C19 substrates as needed.หน้า�